Material Safety Data Sheet
    L-Adrenaline Hydrochloride Solution (1:10,000)
ACC# 45370
  
    | Section 1 - Chemical Product and Company Identification | 
MSDS Name: L-Adrenaline Hydrochloride Solution (1:10,000)
Catalog Numbers:
     S701862
Synonyms:
     L-Epinephrine Hydrochloride;
     L-3,4-Dihydroxy-.alpha.-((methylamino)methyl)benzyl alcohol
     Hydrochloride
Company Identification:
 
 
 
 
 
 
 
Fisher Scientific
 
 
 
 
 
 
 
1 Reagent Lane
 
 
 
 
 
 
 
Fair Lawn, NJ  07410
For information, call:  201-796-7100
Emergency Number:       201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
  
    | Section 2 - Composition, Information on Ingredients | 
  | CAS# | Chemical Name | Percent | EINECS/ELINCS | 
| 7732-18-5 | Water | 99.99 | 231-791-2 | 
|  |  |  | unlisted | 
| 51-43-4 | L-Adrenaline | balance | 200-098-7 | 
  
    | Section 3 - Hazards Identification | 
EMERGENCY OVERVIEW
Appearance: clear, colorless liquid.
 Caution! May cause irritation. May cause fetal
effects based upon animal studies. This is expected to be a low
hazard for usual industrial handling.
Target Organs: None.
Potential Health Effects
     
Eye:
          May cause eye irritation.  Low hazard for normal industrial
          handling.
     
Skin:
          May cause skin irritation. Low hazard for usual industrial handling.
     
Ingestion:
          May cause gastrointestinal irritation with nausea, vomiting and
          diarrhea. Expected to be a low ingestion hazard.
     
Inhalation:
          May cause respiratory tract irritation. Low hazard for usual
          industrial handling.
     
Chronic:
          No information found.
  
    | Section 4 - First Aid Measures | 
     
Eyes:
          Flush eyes with plenty of water for at least 15 minutes, occasionally
          lifting the upper and lower eyelids. Get medical aid.
     
Skin:
          Get medical aid if irritation develops or persists. Flush skin with
          plenty of soap and water.
     
Ingestion:
          If victim is conscious and alert, give 2-4 cupfuls of milk or water.
          Never give anything by mouth to an unconscious person. Get medical
          aid if irritation or symptoms occur.
     
Inhalation:
          Remove from exposure and move to fresh air immediately. If not
          breathing, give artificial respiration. If breathing is difficult,
          give oxygen. Get medical aid if cough or other symptoms appear.
     
Notes to Physician:
          Treat symptomatically and supportively.
  
    | Section 5 - Fire Fighting Measures | 
     
General Information:
          As in any fire, wear a self-contained breathing apparatus in
          pressure-demand, MSHA/NIOSH (approved or equivalent), and full
          protective gear.
     
Extinguishing Media:
          Use extinguishing media most appropriate for the surrounding fire.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
                  Upper: Not available.
     
NFPA Rating:
(estimated) Health: 1; Flammability: 0; Instability: 0
  
    | Section 6 - Accidental Release Measures | 
     
General Information: Use proper personal protective equipment as indicated
                          in Section 8.
     
Spills/Leaks:
          Absorb spill with inert material (e.g. vermiculite, sand or earth),
          then place in suitable container. Clean up spills immediately,
          observing precautions in the Protective Equipment section.
  
    | Section 7 - Handling and Storage | 
     
Handling:
          Wash thoroughly after handling. Use with adequate ventilation.
     
Storage:
          Store in a cool, dry place. Keep containers tightly closed.
  
    | Section 8 - Exposure Controls, Personal Protection | 
     
Engineering Controls:
          Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
  | Chemical Name | ACGIH | NIOSH | OSHA - Final PELs | 
| Water | none listed | none listed | none listed | 
|  | 0.1 mg/m3 TWA  (listed under Tellurium). | 0.1 mg/m3 TWA  (listed under Tellurium).25 mg/m3 IDLH  (listed under Tellurium). | 0.1 mg/m3 TWA  (listed under Tellurium). | 
| L-Adrenaline | none listed | none listed | none listed | 
     
OSHA Vacated PELs:
          Water:
             No OSHA Vacated PELs are listed for this chemical.
          :
             No OSHA Vacated PELs are listed for this chemical.
          L-Adrenaline:
             No OSHA Vacated PELs are listed for this chemical.
     
Personal Protective Equipment
                 
Eyes:
                       Wear appropriate protective eyeglasses or chemical
                       safety goggles as described by OSHA's eye and face
                       protection regulations in 29 CFR 1910.133 or European
                       Standard EN166.
                 
Skin:
                       Wear appropriate protective gloves to prevent skin
                       exposure.
             
Clothing:
                       Wear appropriate protective clothing to prevent skin
                       exposure.
          
Respirators:
                       A respiratory protection program that meets OSHA's 29
                       CFR 1910.134 and ANSI Z88.2 requirements or European
                       Standard EN 149 must be followed whenever workplace
                       conditions warrant respirator use.
  
    | Section 9 - Physical and Chemical Properties | 
Physical State:  Liquid
Appearance:      clear, colorless
Odor:            odorless
pH:              Not available.
Vapor Pressure:  14 mm Hg
Vapor Density:   0.7
Evaporation Rate:>1
Viscosity:       Not available.
Boiling Point:   100 deg C
Freezing/Melting Point:0 deg C
Decomposition Temperature:Not available.
Solubility:      Soluble in water.
Specific Gravity/Density:1.0
Molecular Formula:C9H11NO3
Molecular Weight:181.0819
  
    | Section 10 - Stability and Reactivity | 
     
Chemical Stability:
          Stable under normal temperatures and pressures.
     
Conditions to Avoid:
          None reported.
     
Incompatibilities with Other Materials:
          None reported.
     
Hazardous Decomposition Products:
          None.
     
Hazardous Polymerization: Will not occur.
  
    | Section 11 - Toxicological Information | 
     
RTECS#:
     
CAS# 7732-18-5:
ZC0110000
     
CAS#  unlisted.
     
CAS# 51-43-4:
DO2625000
     
LD50/LC50:
          CAS# 7732-18-5:
      Oral, rat: LD50 =
          >90 mL/kg;
          
 CAS# :
          
 CAS# 51-43-4:
      Skin, rat: LD50
          = 62 mg/kg;
     
Carcinogenicity:
       CAS#    7732-18-5:
          Not listed by ACGIH, IARC, NTP, or CA Prop 65.
       CAS# :
          Not listed by ACGIH, IARC, NTP, or CA Prop 65.
       CAS#      51-43-4:
          Not listed by ACGIH, IARC, NTP, or CA Prop 65.
     
Epidemiology:
          No data available.
     
Teratogenicity:
L-Adrenaline HCl is an experimental teratogen.
     
Reproductive Effects:
L-Adrenaline HCl has caused fetal effects in experiments
with laboratory animals.
     
Mutagenicity:
          No data available.
     
Neurotoxicity:
          No data available.
     
Other Studies:
  
    | Section 12 - Ecological Information | 
          No information available.
  
    | Section 13 - Disposal Considerations | 
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: CAS# 51-43-4: waste number
P042.
RCRA U-Series: None listed.
  
    | Section 14 - Transport Information | 
  |  | US DOT | Canada TDG | 
| Shipping Name: | Not regulated as a hazardous material | No information available. | 
| Hazard Class: |  |  | 
| UN Number: |  |  | 
| Packing Group: |  |  | 
  
    | Section 15 - Regulatory Information | 
 US FEDERAL
     
TSCA
     CAS# 7732-18-5 is listed on the TSCA inventory.
     CAS#  is not listed on the TSCA inventory.
     It is for research and development use only.
     CAS# 51-43-4 is listed on the TSCA inventory.
        
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
        
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
        
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
        
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
        
CERCLA Hazardous Substances and corresponding RQs
     CAS# 51-43-4: 1000 lb final RQ; 454 kg final RQ
        
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
        
SARA Codes
     CAS # 51-43-4: acute, chronic.
        
Section 313
     No chemicals are reportable under Section 313.
     
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
     
Clean Water Act:
     None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
     None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
     
OSHA:
     None of the chemicals in this product
are considered highly hazardous by OSHA.
 
STATE
          CAS#    7732-18-5 is not present on
     state lists from CA, PA, MN, MA, FL, or NJ.
          CAS#  can be found on the following
     state right to know lists: California, (listed as Tellurium), New
     Jersey, (listed as Tellurium), Pennsylvania, (listed as Tellurium),
     Minnesota, (listed as Tellurium), Massachusetts, (listed as
     Tellurium).
          CAS#      51-43-4 can be found on the
     following state right to know lists: New Jersey, Pennsylvania,
     Massachusetts.
 
California Prop 65
     
California No Significant Risk Level:
     None of the chemicals in this product are listed.
 
European/International Regulations
     European Labeling in Accordance with EC Directives
          Hazard Symbols:
      Not available.
          
Risk Phrases:
          
Safety Phrases:
   
WGK (Water Danger/Protection)
     CAS# 7732-18-5: No information available.
     CAS# : No information available.
     CAS# 51-43-4: 3
   Canada - DSL/NDSL
     CAS# 7732-18-5 is listed on Canada's DSL List.
     CAS# 51-43-4 is listed on Canada's DSL List.
   Canada - WHMIS
     WHMIS: Not available.
   Canadian Ingredient Disclosure List
     CAS#  (listed as Tellurium) is listed on the Canadian Ingredient Disclosure List.
  
    | Section 16 - Additional Information | 
     MSDS Creation Date:  9/02/1997  
Revision #3 Date:  7/29/2002
     The information above is believed to be accurate and represents the best
     information currently available to us. However, we make no warranty of
     merchantability or any other warranty, express or implied, with respect to
     such information, and we assume no liability resulting from its use. Users
     should make their own investigations to determine the suitability of the
     information for their particular purposes. In no event shall Fisher be liable
     for any claims, losses, or damages of any third party or for lost profits
     or any special, indirect, incidental, consequential or exemplary
     damages, howsoever arising, even if Fisher has been advised of
     the possibility of such damages.